| Directive ID | Subject | Effective Period |
| NPR 1040.1 | NASA Continuity of Operations (COOP) Planning Procedural Requirements w/Change 1 (03/29/04) | July 3, 2003 to July 3, 2010 |
| NPR 1080.1A | Requirements for the Conduct of NASA Research and Technology (R&T) | May 30, 2008 to May 30, 2013 |
| NPR 1210.1A | Procedures for Use of Monetary Gifts and Donations by NASA | February 23, 2005 to February 23, 2010 |
| NPR 1371.1 | Requests For Waivers Of The Residence Abroad Requirements For Exchange Visitors Sponsored By NASA Contractors And Grantees w/Change 2 (Revalidated January 23, 2008) | November 26, 1997 to February 21, 2013 |
| NPR 1371.2A | Procedural Requirements for Processing Requests for Access to NASA Installations or Facilities by Foreign Nationals or U.S. Citizens Who are Reps of Foreign Entities w/Change 1 (3/29/04) | April 7, 2003 to October 7, 2010 |
| NPR 1382.1 | NASA Privacy Procedural Requirements | August 10, 2007 to August 10, 2012 |
| NPR 1385.1 | Public Appearances of NASA Astronauts and Other Personnel w/Change 1 (Revalidated 01/07/05) | January 7, 2000 to January 7, 2010 |
| NPR 1387.1 | NASA Exhibits Program w/Change 1 (Revalidated 01/08/04) | January 9, 1999 to November 28, 2009 |
| NPR 1400.1D | NASA Directives Procedural Requirements, with Change 5 (11/19/2009) | February 18, 2007 to February 18, 2012 |
| NPR 1441.1D | NASA Records Retention Schedules (w/Change 5, 6/26/09) | February 24, 2003 to February 24, 2013 |
| NPR 1450.10D | NASA Correspondence Management and Communications Standards and Style w/Change 1 (12/30/2008) | March 24, 2006 to March 24, 2011 |
| NPR 1450.4G | Handling Congressional Correspondence And Information Concerning Congressional Activities (Revalidated 07/20/07) | October 31, 2001 to October 31, 2012 |
| NPR 1600.1 | NASA Security Program Procedural Requirements w/Change 2 (4/01/2009) | November 3, 2004 to November 3, 2014 |
| NPR 1620.2 | Physical Security Vulnerability Risk Assessments | July 15, 2004 to April 15, 2010 |
| NPR 1620.3 | Physical Security Requirements for NASA Facilities and Property | August 12, 2004 to December 12, 2009 |
| NPR 1660.1 | Counterintelligence (CI)/Counterterrorism (CT) Procedural Requirements | December 21, 2004 to December 21, 2009 |
| NPR 1800.1C | NASA Occupational Health Program Procedures | October 6, 2009 to October 6, 2014 |
| NPR 1810.1A | Health Services for International Travel or Assignment | August 2, 2006 to August 2, 2011 |
| NPR 1840.1 | Management of Workers' Compensation Injuries and Illnesses w/Change 1 | August 23, 2001 to December 31, 2009 |
| NPR 1900.3B | Ethics Program Management | April 23, 2007 to April 23, 2012 |
| NPR 2081.1 | Nondiscrimination in Federally Assisted and Conducted Programs | February 17, 2004 to December 17, 2009 |
| NPR 2092.1A | Distribution of Royalties Received by NASA from the Licensing or Assignment of Inventions (REVALIDATED 8/12/08) | August 7, 2003 to August 12, 2013 |
| NPR 2190.1 | NASA Export Control Program - Revalidated w/changes February 1, 2007 | April 10, 2003 to April 10, 2013 |
| NPR 2200.2B | Requirements for Documentation, Approval, and Dissemination of NASA Scientific and Technical Information | March 25, 2005 to March 25, 2010 |
| NPR 2210.1A | External Release of NASA Software w/Change 1 (3/29/04) | January 4, 2002 to December 4, 2009 |
| NPR 2570.1B | NASA Radio Frequency (RF) Spectrum Management Manual | December 5, 2008 to December 5, 2013 |
| NPR 2800.1B | Managing Information Technology | March 20, 2009 to March 20, 2014 |
| NPR 2810.1A | Security of Information Technology | May 16, 2006 to May 16, 2011 |
| NPR 2830.1 | NASA Enterprise Architecture Procedures | February 9, 2006 to February 9, 2011 |
| NPR 3100.1A | Management of the Senior Executive Service (SES) | March 9, 2007 to March 9, 2012 |
| NPR 3300.1B | Appointment of Personnel To/From NASA | May 8, 2009 to May 8, 2014 |
| NPR 3317.1A | Senior Executive Service Career Appointee Merit Staffing in NASA | March 13, 2007 to March 13, 2012 |
| NPR 3319.1A | Management of Senior Scientific and Technical (ST) and other Senior Level (SL) Positions | April 23, 2007 to April 23, 2012 |
| NPR 3330.1A | NASA Career Transition Assistance Plan | June 6, 2006 to June 6, 2011 |
| NPR 3335.1G | Internal Placement of NASA Employees | July 18, 2005 to July 18, 2010 |
| NPR 3351.1A | Reduction in Force | June 6, 2006 to June 1, 2011 |
| NPR 3400.1 | Training and Development for the NASA Legal Staff | January 27, 2005 to April 27, 2010 |
| NPR 3430.1C | NASA Employee Performance Communication System (EPCS) - EFFECTIVE MAY 1, 2007 w/Change 5 (5/27/09) | May 1, 2007 to May 1, 2012 |
| NPR 3432.1 | Performance Based Reduction In Grade or Removal Actions (Revalidated with Change 1 03/02/2006) | May 7, 1999 to March 31, 2011 |
| NPR 3435.1B | NASA Performance Management System for the Senior Executive Service | March 5, 2008 to March 5, 2013 |
| NPR 3451.1B | NASA Awards and Recognition Program | June 4, 2009 to June 4, 2014 |
| NPR 3511.1 | Position Management and Classification | September 29, 2006 to September 29, 2011 |
| NPR 3530.1C | NASA Pay and Compensation Policy | January 12, 2009 to January 12, 2014 |
| NPR 3600.1A | Attendance and Leave | April 24, 2006 to April 24, 2011 |
| NPR 3711.1 | Federal Employee Labor Management Relations Program (Revalidated w/Change 1 05/05/2006) | May 7, 1999 to May 7, 2011 |
| NPR 3713.1A | Reasonable Accommodations Procedures | March 28, 2008 to March 28, 2013 |
| NPR 3713.2 | Alternative Dispute Resolution for Discrimination Complaints | May 8, 2009 to May 8, 2014 |
| NPR 3713.3 | Anti-Harassment Procedures | October 6, 2009 to October 6, 2014 |
| NPR 3752.1 | Disciplinary and Adverse Actions (Revalidated w/Change 1 05/05/2006) | May 7, 1999 to May 7, 2011 |
| NPR 3771.1 | Grievance System (Revalidated w/Change 1 05/05/2006) | May 7, 1999 to May 7, 2011 |
| NPR 3792.1B | Plan for a Drug-Free Workplace (REVALIDATED w/Change 1 12/06/06) | July 29, 2006 to July 29, 2011 |
| NPR 3800.1 | Employee Benefits | May 16, 2005 to May 16, 2010 |
| NPR 4100.1D | NASA Materials Inventory Management Manual (Revalidated 2/9/06) | July 29, 1999 to July 29, 2011 |
| NPR 4200.1F | NASA Equipment Management Procedural Requirements | November 14, 2006 to November 14, 2011 |
| NPR 4200.2B | Equipment Management Manual for Property Custodians w/Change 1, 9/11/03 | September 11, 1998 to May 19, 2010 |
| NPR 4300.1A | NASA Personal Property Disposal Procedural Requirements (Revalidated 2/17/06 with Change 1) | July 19, 1999 to July 19, 2011 |
| NPR 4310.1 | Identification and Disposition of NASA Artifacts (Revalidated w/Change 2 1/31/06) | March 16, 1999 to March 16, 2011 |
| NPR 5100.4B | Federal Acquisition Regulation Supplement (NASA/FAR Supplement) [48 CFR 1800-1899] (REVALIDATED 9/16/2008) | August 31, 1997 to December 31, 2013 |
| NPR 5101.33A | Procurement Advocacy Programs w/Change 2 (10/04/04), Revalidated 2/25/05 | May 19, 2000 to May 19, 2010 |
| NPR 5200.1D | Industrial Labor Relations Manual (Revalidated May 31, 2007 with admin. changes) | June 23, 1997 to July 8, 2012 |
| NPR 5800.1E | Grant And Cooperative Agreement Handbook (14 CFR 1260) | October 19, 2000 to March 31, 2011 |
| NPR 5810.1 | Standard Format for NASA Research Announcements (NRAs) and other Announcements for Grants and Cooperative Agreements | October 18, 2004 to November 30, 2009 |
| NPR 5900.1 | NASA Spare Parts Acquisition w/Change 2 (12/19/08) | October 28, 2003 to December 31, 2013 |
| NPR 6000.1G | Requirements for Packaging, Handling, and Transportation for Aeronautical and Space Systems, Equipment, and Associated Components | March 28, 2005 to March 28, 2010 |
| NPR 6200.1C | NASA Transportation and General Traffic Management | October 8, 2008 to October 8, 2013 |
| NPR 7100.1 | Protection of Human Research Subjects (Revalidated 7/7/08) | March 28, 2003 to June 7, 2013 |
| NPR 7120.5D | NASA Space Flight Program and Project Management Requirements | March 6, 2007 to March 6, 2012 |
| NPR 7120.6 | Lessons Learned Process | March 22, 2005 to March 22, 2010 |
| NPR 7120.7 | NASA Information Technology and Institutional Infrastructure Program and Project Management Requirements | November 3, 2008 to November 3, 2013 |
| NPR 7120.8 | NASA Research and Technology Program and Project Management Requirements | February 5, 2008 to February 5, 2013 |
| NPR 7123.1A | NASA Systems Engineering Processes and Requirements | March 26, 2007 to March 26, 2012 |
| NPR 7150.2 | NASA Software Engineering Requirements | September 27, 2004 to December 27, 2009 |
| NPR 7500.1 | NASA Technology Commercialization Process w/ Change 1 (4/9/04) | December 20, 2001 to July 20, 2010 |
| NPR 7900.3B | Aircraft Operations Management | June 14, 2007 to June 14, 2012 |
| NPR 8000.4A | Agency Risk Management Procedural Requirements | December 16, 2008 to December 16, 2013 |
| NPR 8020.12C | Planetary Protection Provisions for Robotic Extraterrestrial Missions | April 27, 2005 to April 27, 2010 |
| NPR 8530.1A | Affirmative Procurement Program and Plan for Environmentally Preferable Products (REVALIDATED 4/3/09 w/change 3) | June 4, 2004 to June 4, 2014 |
| NPR 8553.1B | NASA Environmental Management System | September 22, 2009 to September 22, 2014 |
| NPR 8570.1 | Energy Efficiency and Water Conservation w/Change 2 (4/04/08) REVALIDATED | March 15, 2001 to April 4, 2013 |
| NPR 8580.1 | Implementing The National Environmental Policy Act And Executive Order 12114 | November 26, 2001 to November 26, 2010 |
| NPR 8590.1 | NASA Environmental Compliance and Restoration (ECR) Program | June 14, 2007 to June 14, 2012 |
| NPR 8621.1B | NASA Procedural Requirements for Mishap and Close Call Reporting, Investigating, and Recordkeeping w/Change 4 (11/02/2009) | May 23, 2006 to May 23, 2011 |
| NPR 8705.2B | Human-Rating Requirements for Space Systems | May 6, 2008 to May 6, 2013 |
| NPR 8705.4 | Risk Classification for NASA Payloads (Revalidated July 9, 2008) | June 14, 2004 to July 9, 2013 |
| NPR 8705.5 | Probabilistic Risk Assessment (PRA) Procedures for NASA Programs and Projects | July 12, 2004 to December 12, 2009 |
| NPR 8705.6A | Safety and Mission Assurance Audits, Reviews, and Assessments | April 9, 2009 to April 9, 2014 |
| NPR 8715.1 | NASA Occupational Safety and Health Programs w/Change 3 (02/13/06) | August 9, 1999 to September 30, 2011 |
| NPR 8715.2A | NASA Emergency Preparedness Procedural Requirements | January 9, 2009 to January 9, 2014 |
| NPR 8715.3C | NASA General Safety Program Requirements (w/Change 4 dated 7/20/09) | March 12, 2008 to March 12, 2013 |
| NPR 8715.5 | Range Safety Program | July 8, 2005 to July 8, 2010 |
| NPR 8715.6A | NASA Procedural Requirements for Limiting Orbital Debris (w/ Change 1 - 5/14/09) | May 14, 2009 to May 14, 2014 |
| NPR 8715.7 | Expendable Launch Vehicle Payload Safety Program | May 30, 2008 to May 30, 2013 |
| NPR 8735.1B | Procedures For Exchanging Parts, Materials, and Safety Problem Data Utilizing the Government-Industry Data Exchange Program and NASA Advisories | December 28, 2007 to December 28, 2012 |
| NPR 8735.2A | Management of Government Quality Assurance Functions for NASA Contracts | August 2, 2006 to August 2, 2011 |
| NPR 8800.15A | Real Estate Management Program Implementation Manual | September 1, 1998 to July 1, 2010 |
| NPR 8810.1 | Master Planning Procedural Requirements | April 28, 2005 to April 28, 2010 |
| NPR 8820.2F | Facility Project Requirements | January 28, 2008 to January 28, 2013 |
| NPR 8831.2E | Facilities Maintenance and Operations Management | November 18, 2008 to November 18, 2013 |
| NPR 8900.1 | Health and Medical Requirements for Human Space Exploration | May 23, 2008 to May 23, 2013 |
| NPR 8910.1B | Care and Use of Animals | October 7, 2009 to October 7, 2014 |
| NPR 9010.1 | Financial Management Requirements Overview | September 30, 2008 to September 30, 2013 |
| NPR 9010.2 | Financial Management Operating Procedures and the Continuous Monitoring Program | September 30, 2008 to September 30, 2013 |
| NPR 9010.3 | Financial Management Internal Control | September 30, 2008 to September 30, 2013 |
| NPR 9020.1 | Definitions of Financial Management Terms | September 30, 2008 to September 30, 2013 |
| NPR 9050.1A | Official Representational Fund w/Changes 1 - 4 (11/15/05) | November 4, 2002 to November 4, 2012 |
| NPR 9050.2 | Advances and Prepayments | September 30, 2008 to September 30, 2013 |
| NPR 9050.3 | The Antideficiency Act | September 30, 2008 to September 30, 2013 |
| NPR 9050.4 | Cash Management and Improper Payments | September 30, 2008 to September 30, 2013 |
| NPR 9050.5 | Cash Management for Contracts | September 30, 2008 to September 30, 2013 |
| NPR 9060.1 | Cost Accruals | September 30, 2008 to September 30, 2013 |
| NPR 9090.1 | Reimbursable Agreements | September 30, 2008 to September 30, 2013 |
| NPR 9095.1 | Working Capital Fund Policies and Requirements | September 30, 2008 to September 30, 2013 |
| NPR 9130.1 | NASA Financial Information Systems | September 30, 2008 to September 30, 2013 |
| NPR 9200.1 | Accounting General Overview | September 30, 2008 to September 30, 2013 |
| NPR 9210.1 | Cash and Fund Balance with Treasury | September 30, 2008 to September 30, 2013 |
| NPR 9220.1 | Journal Voucher Preparation and Approval and Intragovernmental Transactions | September 30, 2008 to September 30, 2013 |
| NPR 9250.1 | Property, Plant, and Equipment and Operating Materials and Supplies | September 30, 2008 to September 30, 2013 |
| NPR 9260.1 | Revenue, Unfunded Liabilities and Other Liabilities | September 30, 2008 to September 30, 2013 |
| NPR 9290.1 | Special Accounts | September 30, 2008 to September 30, 2013 |
| NPR 9310.1 | External Reports - Accounting | September 30, 2008 to September 30, 2013 |
| NPR 9311.1 | External Reports - Budget | September 30, 2008 to September 30, 2013 |
| NPR 9420.1 | Budget Formulation | December 24, 2008 to December 24, 2013 |
| NPR 9470.1 | Budget Execution | December 24, 2008 to December 24, 2013 |
| NPR 9501.2D | NASA Contractor Financial Management Reporting (Revalidated w/Change 1 02/16/2006) | May 23, 2001 to May 23, 2011 |
| NPR 9610.1 | Accounts Receivable | September 30, 2008 to September 30, 2013 |
| NPR 9615.1 | Accounts Payable | September 30, 2008 to September 30, 2013 |
| NPR 9620.1 | Payroll | September 30, 2008 to September 30, 2013 |
| NPR 9631.1 | Disbursements | September 30, 2008 to September 30, 2013 |
| NPR 9635.1 | Billings and Collections | September 30, 2008 to September 30, 2013 |
| NPR 9645.1 | Claims for Erroneous Payment of Pay and Allowances, Travel and Transportation, Relocation Expenses and Allowances | September 30, 2008 to September 30, 2013 |
| NPR 9660.1 | Vital Records and Emergency Operations | September 30, 2008 to September 30, 2013 |
| NPR 9680.1 | NASA's Management of Grants and Cooperative Agreements | October 31, 2008 to October 31, 2013 |
| NPR 9690.1 | Investments | September 30, 2008 to September 30, 2013 |
| NPR 9700.1 | Travel w/ change 1 1/27/09 | September 30, 2008 to September 30, 2013 |